丰县人民医院晚期恶性实体肿瘤受试者招募
<section style="background-color: rgb(255, 252, 247);box-sizing: border-box;font-style: normal;font-weight: 400;text-align: justify;font-size: 16px;color: rgb(62, 62, 62);"><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p><section style="text-align: center;box-sizing: border-box;"><section style="display: inline-block;width: 294px;height: 199px;vertical-align: top;overflow: hidden;background-repeat: no-repeat;background-attachment: scroll;background-image: url(https://bbs.221700.com/plugin.php?id=wcn_editor:wx_img&url=https://mmbiz.qpic.cn/mmbiz_png/HlZK2TpeY5R3aKJCLnb1KIPVFKxxBzCpbcgsOayqVPI7oqTr6ia8NVhV4v25qENdMCd5PnNxFRZzh52yfuG7t3Q/640?wx_fmt=png);background-size: contain !important;background-position: 50% 50% !important;box-sizing: border-box;"><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 3;box-sizing: border-box;"><section style="margin: 15% 0px 0px;box-sizing: border-box;"><section style="text-align: justify;color: rgb(247, 193, 82);letter-spacing: 1px;box-sizing: border-box;"><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p></section></section></section></section><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 2;box-sizing: border-box;"><section style="font-size: 32px;color: rgb(155, 188, 120);letter-spacing: 1px;box-sizing: border-box;"><p style="margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span leaf="">（受试者招募）</span></strong></p></section></section></section><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 2;box-sizing: border-box;"><section style="justify-content: center;display: flex;flex-flow: row;margin: 5px 0px 0px;box-sizing: border-box;"><section style="display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 10px 8px;border-top: 1px solid rgb(182, 211, 151);box-sizing: border-box;"><section style="text-align: justify;color: rgb(155, 188, 120);letter-spacing: 1px;box-sizing: border-box;"><p style="text-align: center;white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">+ 丰县人民医院 +</span></p></section></section></section></section></section></section></section><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="height: auto;z-index: 2;box-sizing: border-box;"><section style="text-align: center;justify-content: center;display: flex;flex-flow: row;margin: 10px 0px -12px;box-sizing: border-box;"><section style="display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 8px 0px 0px;box-sizing: border-box;"><section style="font-size: 19px;margin: 0px 0%;box-sizing: border-box;"><section style="display: inline-block;border: 1px solid rgb(182, 211, 151);background-color: rgb(182, 211, 151);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 16px;color: rgb(255, 255, 255);box-sizing: border-box;"><p style="margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span leaf="">患</span></strong></p></section></section></section><section style="display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 8px 0px 0px;box-sizing: border-box;"><section style="font-size: 19px;margin: 0px 0%;box-sizing: border-box;"><section style="display: inline-block;border: 1px solid rgb(255, 211, 122);background-color: rgb(255, 211, 122);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 16px;color: rgb(255, 255, 255);box-sizing: border-box;"><p style="margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span leaf="">者</span></strong></p></section></section></section><section style="display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 8px 0px 0px;box-sizing: border-box;"><section style="font-size: 19px;margin: 0px 0%;box-sizing: border-box;"><section style="display: inline-block;border: 1px solid rgb(182, 211, 151);background-color: rgb(182, 211, 151);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 16px;color: rgb(255, 255, 255);box-sizing: border-box;"><p style="margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span leaf="">招</span></strong></p></section></section></section><section style="display: inline-block;vertical-align: bottom;width: auto;align-self: flex-end;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px;box-sizing: border-box;"><section style="font-size: 19px;margin: 0px 0%;box-sizing: border-box;"><section style="display: inline-block;border: 1px solid rgb(255, 211, 122);background-color: rgb(255, 211, 122);width: 1.8em;height: 1.8em;line-height: 1.8em;border-radius: 100%;margin-left: auto;margin-right: auto;font-size: 16px;color: rgb(255, 255, 255);box-sizing: border-box;"><p style="margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span leaf="">募</span></strong></p></section></section></section></section></section></section><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: auto;box-sizing: border-box;"><section style="text-align: center;justify-content: center;display: flex;flex-flow: row;margin: -5px 0px 0px;box-sizing: border-box;"><section style="display: inline-block;width: 90%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;height: auto;background-color: rgb(255, 255, 255);padding: 30px 20px 20px;border-style: dashed;border-width: 0px;border-color: rgb(255, 211, 122);box-shadow: rgb(254, 240, 210) 0px 0px 5px 0px;box-sizing: border-box;"><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 4;box-sizing: border-box;"><section style="text-align: justify;line-height: 2;letter-spacing: 2px;padding: 0px;box-sizing: border-box;"><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">尊敬的患者及家属朋友：</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">经国家食品药品监督管理局批准，我院正在开展一项“评估克非奇拜单抗注射液联合特瑞普利单抗注射液用于既往接受抗PD-1/PD-L1类药物治疗失败的不可切除或转移性微卫星高度不稳定(MSI-H) 或错配修复缺陷（dMMR）的晚期恶性实体瘤患者的II期、单臂、多中心、开放标签临床研究”，该药物为治疗用生物制品1类，现已得到本院的伦理委员会审批同意。</span></p></section></section></section></section></section></section></section><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf=""><br/></span></p><section style="text-align: center;justify-content: center;display: flex;flex-flow: row;margin: 10px 0px;box-sizing: border-box;"><section style="display: inline-block;width: 90%;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(255, 255, 255);padding: 20px;height: auto;box-shadow: rgb(254, 240, 210) 0px 0px 5px 0px;box-sizing: border-box;"><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 4;box-sizing: border-box;"><section style="text-align: justify;line-height: 2;letter-spacing: 2px;padding: 0px;box-sizing: border-box;"><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="color: rgb(230, 52, 82);box-sizing: border-box;"><span leaf="">参加本研究的基本条件：</span></span></strong></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">1、年满18周岁。</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">2、ECOG体能状态评分为0-1分。</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">3、根据RECIST v1.1评估确定，至少有1个可测量病灶。</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">4、既往接受抗PD-1/PD-L1类药物单药治疗或联合（同步或序贯）其他系统性治疗失败的不可切除或转移性晚期MSI-H/dMMR实体瘤，既往系统性治疗方案中仅有1个线数的治疗方案含抗PD-1/PD-L1类药物，结直肠癌既往治疗线数不超过3线，其他实体瘤治疗既往治疗线数不超过2线。</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">5、您的实验室检查，包括血清病毒学检查、血生化、血常规、尿常规、便潜血、甲状腺功能、凝血功能和心电图检查等指标经研究医生确定符合本研究的入选标准。</span></p></section></section></section><section style="justify-content: center;display: flex;flex-flow: row;margin: 10px 0px;box-sizing: border-box;"><section style="display: inline-block;vertical-align: middle;width: 11%;align-self: center;flex: 0 0 auto;height: auto;box-sizing: border-box;"><section style="margin: 0px;box-sizing: border-box;"><section style="background-color: rgb(93, 142, 216);height: 1px;box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section><section style="display: inline-block;vertical-align: middle;width: auto;align-self: center;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;padding: 0px 15px;box-sizing: border-box;"><section style="display: flex;width: 100%;flex-flow: column;box-sizing: border-box;"><section style="z-index: 2;box-sizing: border-box;"><section style="justify-content: center;display: flex;flex-flow: row;box-sizing: border-box;"><section style="display: inline-block;width: auto;vertical-align: top;align-self: flex-start;flex: 0 0 auto;min-width: 5%;max-width: 100%;height: auto;box-sizing: border-box;"><section style="transform: rotateZ(45deg);-webkit-transform: rotateZ(45deg);-moz-transform: rotateZ(45deg);-o-transform: rotateZ(45deg);box-sizing: border-box;"><section style="justify-content: center;display: flex;flex-flow: row;box-sizing: border-box;"><section style="display: inline-block;width: 22px;vertical-align: top;align-self: flex-start;flex: 0 0 auto;background-color: rgb(241, 128, 133);padding: 3px;height: auto;border-radius: 5px;overflow: hidden;box-sizing: border-box;"><section style="transform: rotateZ(315deg);-webkit-transform: rotateZ(315deg);-moz-transform: rotateZ(315deg);-o-transform: rotateZ(315deg);box-sizing: border-box;"><section style="margin: 0px;line-height: 0;box-sizing: border-box;"><section style="max-width: 100%;vertical-align: middle;display: inline-block;line-height: 0;width: 100%;height: auto;box-sizing: border-box;" nodeleaf=""></section></section></section></section></section></section></section></section></section></section></section><section style="display: inline-block;vertical-align: middle;width: 11%;align-self: center;flex: 0 0 auto;height: auto;box-sizing: border-box;"><section style="margin: 0px;box-sizing: border-box;"><section style="background-color: rgb(93, 142, 216);height: 1px;box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section></section><section style="text-align: justify;letter-spacing: 2px;line-height: 2;box-sizing: border-box;"><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">如果您至少符合上述条件，并且愿意参加本次临床研究，请联系丰县人民医院肿瘤科负责医师谢军主任进行详细了解。</span></p><p style="white-space: normal;margin: 0px;padding: 0px;box-sizing: border-box;"><span leaf="">联系电话：15862199928</span></p></section></section></section></section><p style="display: none;"><mp-style-type data-value="10000"></mp-style-type></p><p style="color:#999;font-size:.8em;margin-top:1em">转载声明：本文转载自丰县人民医院订阅号</p><p><br/></p><link rel="stylesheet" href="//bbs.221700.com/source/plugin/wcn_editor/public/wcn_editor_fit.css?v134_EX5" id="wcn_editor_css"/>
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